Carolina Adam

Carolina Adam

🧬 evolutionary biologist

Posts by Collection

portfolio

publications

Genetic diversity and population structure of the semiterrestrial crab Armases benedicti (Brachyura, Sesarmidae) along the North Brazilian coast

Published in Crustaceana, 2024

We conduct population genetics and structure analysis of the semiterrestrial crab Armases benedicti along the North Brazilian coast.

Recommended citation: Adam, C. L., Schubart, C. D., Masunari, S., & Marochi, M. Z. (2024). Genetic diversity and population structure of the semiterrestrial crab Armases benedicti (Brachyura, Sesarmidae) along the North Brazilian coast. Crustaceana, 97(5-9), 553-566..
Download Paper

TRACKing Tandem Repeats: a customizable pipeline for identification and cross-species comparisons

Published in Bioinformatics Advances, 2025

We present TRACK, a user-friendly Snakemake pipeline designed to consolidate the discovery and comparison of tandem repeats (TRs) across species

Recommended citation: Adam, C. L., Rocha, J., Sudmant, P., & Rohlfs, R. (2025). TRACKing tandem repeats: a customizable pipeline for identification and cross-species comparison. Bioinformatics Advances, 5(1), vbaf066.
Download Paper

Hierarchical Genetic Differentiation and Population Structure in the Semiterrestrial Crab Armases Rubripes (Brachyura, Sesarmidae)

Published in Marine Ecology, 2026

Using cytochrome oxidase 1 (COI) data, our results revealed a potential cryptic species complex in Armases rubripes, with Caribbean and Brazilian regions representing separate evolving lineages.

Recommended citation: Adam, C.L., Thiercelin, N., Wawrschin, L., Masunari, S., Schubart, C.D., & Marochi, M.Z. (2026). Hierarchical Genetic Differentiation and Population Structure in the Semiterrestrial Crab Armases Rubripes (Brachyura, Sesarmidae).
Download Paper

A Statistical Framework to Infer the Mutation Model of Tandem Repeat Variants

Published in BioRxiv, 2026

We propose a computational method that leverages ancestral recombination graph (ARG) to estimate the mutation process that drives the evolution of TR loci.

Recommended citation: Luna, L.G.F., Iturbe, S., Adam, C.L., Pope, N.S., Ortega-Del Vecchyo, D., Rohlfs, R. (2026). A Statistical Framework to Infer the Mutation Model of Tandem Repeat Variants.
Download Paper

A Pan-pangenome illuminates complex structural variation and selection in humans, chimpanzees, and bonobos

Published in BioRxiv, 2026

We sequence and assemble 58 haplotypes from four distinct Pan clades to high contiguity, including eight near-T2T genomes. We find that structural variants (SVs) are 170- to 260-fold more likely than single nucleotide variants (SNVs) to exhibit high-impact effects across species, and that human disease-associated tandem repeats (TRs) are expanded and highly diverse in humans, sensitizing our species to TR-expansion disorders.

Recommended citation: Rocha, J.L., Lou, R.N, Adam, C.L., Hebbar, P., Ferguson, S., Bolognini, D., Killilea, A., Hoekzema, K., Guarracino, A., Deng, Y., Soranzo, N., Paten, B., Garrison, E., Pollen, A., Eichler, E., Rohlfs, R.V., Mitchell, M., Sudmant, P.H. (2026). A Pan-pangenome illuminates complex structural variation and selection in humans, chimpanzees, and bonobos.
Download Paper

Tandem repeat variation within and between species reveals signatures of selection in humans and chimpanzees

Published in BioRxiv, 2026

We create a comprehensive TR catalog for seven T2T ape genomes and leverage long-read, population-level data from humans and chimpanzees to identify TR loci with disproportionate divergence-diversity ratios as targets of natural selection.

Recommended citation: Adam, C.L., Rocha, J., Sudmant, P.H., Rohlfs, R.V. (2026). Tandem repeat variation within and between species reveals signatures of selection in humans and chimpanzees.
Download Paper

talks

teaching

Teaching experience 1

Undergraduate course, University 1, Department, 2014

This is a description of a teaching experience. You can use markdown like any other post.

Teaching experience 2

Workshop, University 1, Department, 2015

This is a description of a teaching experience. You can use markdown like any other post.